Description
POSITION SUMMARY:
As a market leader in cfDNA-based diagnostics, we are expanding our Early Cancer Detection (ECD) portfolio to deliver transformative clinical impact at scale. The Senior Director, ECD Product Strategy will lead the strategy, development, and lifecycle management of a portfolio of ECD products, from concept through launch, growth, and optimization.
This role is accountable for defining product vision and strategy, translating unmet clinical and customer needs into differentiated products, and driving execution through strong cross-functional leadership. The Senior Director will build and manage a high-performing product management team and partner closely with R&D, clinical, regulatory, commercial, medical affairs, and operations to ensure successful delivery of business and patient outcomes.
POSITION LOCATION:
This position can be out of our San Carlos, CA office or Remote, USA.
PRIMARY RESPONSIBILITIES:
Product Strategy & Portfolio Leadership
- Own the product vision, strategy, and roadmap for the Early Cancer Detection portfolio, aligned with corporate strategy and long-term growth objectives
- Lead annual and multi-year strategic planning for ECD products, including investment prioritization, sequencing, and resource allocation
- Identify, size, and segment new market opportunities using top-down and bottom-up analyses, incorporating clinical, commercial, and customer insights
- Define clear value propositions and differentiation strategies based on competitive intelligence, customer needs, and evolving standards of care
Product Lifecycle Management
- Lead products across the full lifecycle, from concept and feasibility through development, launch, post-launch optimization, and eventual sunset
- Drive definition of product requirements, success metrics, and launch readiness in partnership with cross-functional teams
- Guide trade-off decisions across performance, features, timelines, and investment, particularly in technically complex genomic and algorithm-driven products
Customer & Market Insights
- Lead qualitative and quantitative customer research with clinicians, health systems, payers, partners, and internal stakeholders
- Translate insights into clear product requirements, roadmap decisions, and business cases
- Monitor competitive landscape, emerging technologies, and regulatory or reimbursement changes impacting early cancer detection
Financial & Business Planning
- Build and oversee robust business cases, including revenue forecasts, unit economics, ROI, and NPV analyses for new and existing products
- Pressure-test assumptions, evaluate sensitivities, and make data-driven investment recommendations
- Partner with finance and commercial leadership to align product strategy with financial objectives
People & Cross-Functional Leadership
- Lead, and develop a team of Product Managers supporting innovation and lifecycle initiatives within Early Cancer Detection
- Establish and scale product management best practices, processes, and metrics
- Act as a senior product leader and influencer across R&D, clinical, regulatory, medical affairs, commercial, and executive leadership
- Clearly communicate product vision, strategy, and priorities to align stakeholders and inspire teams
QUALIFICATIONS:
- Bachelor’s degree required; advanced degree (PhD, MD, or MBA) strongly preferred
- 10+ years of experience in product management, product strategy, consulting, or related roles within diagnostics, biotechnology, medical devices, or health technology
- Prior experience with early cancer detection products strongly preferred
- Demonstrated experience managing products across the full lifecycle, including successful product launches
- Proven people leadership experience, including hiring, coaching, and developing product managers
- Experience developing regulated clinical products and working closely with clinical trials and regulatory pathways
KNOWLEDGE, SKILLS, AND ABILITIES:
- Strategic, analytical thinker with the ability to translate complex data into clear product and business decisions
- Strong market research capabilities, including customer interviews and quantitative analysis
- Comfortable diving deep into technical, algorithmic, and molecular concepts and translating them into customer-facing product features
- Hands-on financial modeling and business case development expertise
- Exceptional cross-functional leadership, communication, and influence skills
- Entrepreneurial mindset with a bias toward action, accountability, and results
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page
Similar jobs
Est. 160,650 USD
POSITION SUMMARY: We are seeking a Senior Clinical Scientist to lead execution of key components of clinical development for our early cancer detection (ECD) program. This role is central to leading study execution, clin…
Est. 187,875 USD
Location: Hybrid in San Carlos, CA preferred but US Remote is considered Position Overview We are seeking a highly experienced Associate Director, CDx Partnership Program Management with a proven track record across a su…
Est. 185,000 USD
Director, Field Translational Science — Oncology Position Summary Natera is shifting disease management worldwide through unprecedented molecular innovation. As the Director of Field Translational Science, you will build…
Est. 157,500 USD
Natera is currently seeking a Bioinformatics Manager to join the Bioinformatics team focused on Oncology Product Development. In this role, the individual will manage a team of Bioinformaticians and Data Scientists and p…
Est. 171,450 USD
Position Summary Natera's mission is to make personalized genetic testing part of the standard of care — enabling earlier, more targeted interventions that lead to longer, healthier lives. For people who have faced cance…
Est. 210,400 USD
Position Summary We are seeking a strategic, relationship-driven leader to serve as our Director of Alliance Management, joining a high-visibility team at the intersection of BioPharma strategy and operational excellence…
Est. 158,950 USD
POSITION SUMMARY: This Senior Manager, Clinical Trial is responsible for managing all aspects of clinical trials to support the development, validation, and commercialization non-invasive molecular diagnostic tests. This…
Est. 150,000 USD
Join our dynamic team as a Senior Sales Engineer where you will provide vital technical support to our sales team during pre-sales and customer expansion activities. You’ll act as the go-to technical resource for securit…
Est. 191,600 USD
POSITION SUMMARY: We are seeking a Staff Machine Learning Scientist – Translational AI to provide technical leadership at the intersection of deep learning foundation models, computational biology, and molecular diagnost…
Est. 274,250 USD
The Medical Director, Genitourinary Oncology is a critical leadership role responsible for advancing clinical development, shaping medical strategy, contributing to foundational clinical evidence generation, and engaging…
Est. 122,150 USD
Natera is a global leader in cell-free DNA testing. We measure fetal, tumor, or donor cfDNA at the molecular level to help inform personalized health care decisions with a non-invasive test. We are looking for a highly m…
Est. 184,300 USD
Natera is seeking an Associate Director to lead a team of Bioinformatics Scientists in our Women's Health and Organ Health research organization. You will oversee the scientific planning and execution of research and ass…
Est. 131,400 USD
Natera is a global leader in cell-free DNA testing. We measure fetal, tumor, or donor cfDNA at the molecular level to help inform personalized health care decisions with a non-invasive test. We are looking for a highly m…
Est. 176,950 USD
Natera is seeking a Staff Scientist to join our Early Research Team. The primary focus of this role is to independently lead the research and development of novel next-generation sequencing (NGS) technologies. In this ro…
Est. 128,400 USD
POSITION SUMMARY: Natera is seeking an innovative Scientist, R&D to join Natera’s Oncology Product Development Team. We are looking for a meticulous and dedicated candidate with experience in next generation sequenci…
Est. 248,000 USD
LOCATION: The territory includes NH, ME, PA, NJ, NY, CT, MA, NH, VT, OH, and parts of PA. Ideal candidate must reside the territory. The Director of National Accounts will focus on developing and implementing high-level…
Est. 140,650 USD
POSITION SUMMARYWe are seeking a strategic Senior Salesforce Product Manager to drive the product vision, roadmap, and execution of our Salesforce platform initiatives while championing user-centric design and data-drive…
Est. 120,500 USD
Position Summary The Alliance Manager will play a critical role in enabling successful external collaborations that accelerate the translation of scientific discoveries into clinically actionable molecular solutions. Thi…
Est. 177,500 USD
LOCATION: The territory for this role spans multiple markets, including Akron, Pittsburgh, and Western Pennsylvania, and extends south to cover portions of Maryland and West Virginia. The Clinical Field Specialist will p…
Est. 173,250 USD
Natera is currently seeking a Bioinformatics Manager to join the Bioinformatics team focused on Oncology Product Development. In this role, the individual will manage a team of Bioinformaticians and Data Scientists and p…
Est. 252,500 USD
Associate/Laboratory Director of Oncology, Comprehensive Genomic Profiling Position Summary As an Associate Lab Director or Lab Director of Oncology, you have clinical oversight of Natera’s laboratory testing related to…
Est. 215,000 USD
LOCATION: This role will cover Northern California. Ideally, we are looking for someone in the San Francisco Bay Area. We’re looking for a dynamic Clinical Oncology Specialist (COS) to join our newly established Breast O…
Est. 133,850 USD
Location: Remote or On-Site in Boulder, CO (Foresight Dx business unit, a Natera company) Foresight Diagnostics is a molecular diagnostics company pioneering non-invasive cancer detection through highly sensitive, cell-f…
Est. 294,175 USD
Location: Remote with ~40% domestic and international travel Shape the future of cancer care as a Medical Director, Skin/IO at Natera. In this strategic leadership role, you will provide medical expertise and scientific…
Est. 78,500 USD
POSITION SUMMARY: The Product Development Sr. Research Associate will contribute to the design, execution and participation in experiments/tasks to support oncology product development and verification and validation (V&…
Est. 230,600 USD
This is an exciting opportunity to lead and grow the Data Science and Bioinformatics function supporting Natera's Women's Health and Organ Health product portfolios. In this role, you will build the bioinformatics capabi…
Est. 130,250 USD
POSITION SUMMARY: The Manager, Clinical Trials will be responsible for managing all aspects of clinical trials from start-up through close-out. The Clinical Trial Manager should have experience in managing all aspects of…
Est. 157,500 USD
Natera is seeking a Manager, Bioinformatics to lead production support for the bioinformatics and data science algorithms behind our Women's Health and Organ Health products. You will lead a team of Data and Bioinformati…
Est. 155,350 USD
POSITION SUMMARY: Natera is a global leader in cell-free DNA testing. We measure fetal, tumor, or donor cfDNA at the molecular level to help inform personalized health care decisions with a non-invasive test. The Natera…
Est. 209,600 USD
This is an exciting opportunity to lead and grow the Data Science and Bioinformatics function supporting Natera's Women's Health and Organ Health product portfolios. In this role, you will build the bioinformatics capabi…